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However, we cannot suggest that mesna has a protective effect for hemorrhagic cystitis. Prospective studies are needed to determine the career pfizer effect of mesna. NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address. Request Permissions Skip to main content googletag.

MATERIALS AND METHODSWe retrospectively analyzed the data of 1156 patients treated with CYC for severe manifestations of various rheumatologic diseases. View this table:View inlineView popupTable 1.

Clinical characteristics of the 1018 patients treated with CYC. View this contraction inlineView popupTable 2. Urinary tract toxicityWe identified 17 patients (1. Predictors of hemorrhagic cystitisIn Table 3, univariate analysis for predictors of hemorrhagic cystitis are summarized.

Cox proportional hazard regression analysis of predisposing factors for hemorrhagic cystitis occurrence. Incidence and prevention of bladder toxicity from cyclophosphamide in the treatment career pfizer rheumatic diseases: a data-driven review.

OpenUrlCrossRefPubMedAptekar RG, Atkinson JP, Decker JL, Wolff SM, Chu EW. Bladder toxicity with chronic oral cyclophosphamide therapy in nonmalignant disease. OpenUrlCrossRefPubMedPlotz Career pfizer, Klippel JH, Decker JL, Grauman D, Wolff B, Brown BC, et al. Bladder complications in patients receiving cyclophosphamide for systemic lupus erythematosus or rheumatoid arthritis.

OpenUrlCrossRefPubMedTalar-Williams C, Career pfizer YM, Walther MM, Linehan WM, Hallahan CW, Lubensky I, et al. Cyclophosphamide-induced cystitis and bladder cancer in patients with Wegener granulomatosis. OpenUrlCrossRefPubMedPedersen-Bjergaard J, Ersboll J, Hansen VL, Sorensen BL, Christoffersen K, Hou-Jensen K, et al. Cyclophosphamide teratogenesis: a review. Cyclophosphamide-induced gonadal toxicity: a treatment dilemma in patients with lupus nephritis.

Side-effects of intravenous cyclophosphamide pulse therapy. Comparative pharmacologic study in vitro and in vivo with cyclophosphamide (NSC-26271), cyclophosphamide metabolites, and plain nitrogen mustard compounds. OpenUrlPubMedBrock N, Stekar J, Pohl J, Niemeyer U, Scheffler G. Acrolein, the causative factor career pfizer urotoxic side-effects of cyclophosphamide, ifosfamide, johnson science and sufosfamide.

OpenUrlPubMedBatista CK, Brito GA, Souza Diet pill, Leitao BT, Cunha FQ, Ribeiro RA.

A model of hemorrhagic cystitis induced with acrolein career pfizer mice. In: Dorr RT, Von Hoff DD, eds. Cancer chemotherapy handbook, 2nd ed. Dechant KL, Brogden RN, Pilkington T, Faulds D. A review of its antineoplastic activity, pharmacokinetic properties and therapeutic efficacy in cancer. OpenUrlCrossRefPubMedScheef W, Klein HO, Brock N, Burkert H, Gunther U, Hoefer-Janker H, et al. Controlled clinical studies with an antidote against the urotoxicity of oxazaphosphorines: preliminary do my wife. OpenUrlPubMedBryant BM, Career pfizer M, Ford HT, Career pfizer IE.

Prevention of isophosphamide-induced urothelial toxicity with 2-mercaptoethane sulphonate sodium (mesnum) career pfizer patients with advanced carcinoma. OpenUrlPubMedSakurai M, Saijo N, Shinkai T, Eguchi K, Sasaki Y, Career pfizer T, et al. The protective effect of 2-mercapto-ethane sulfonate (MESNA) on hemorrhagic cystitis induced by high-dose ifosfamide treatment tested by a randomized crossover trial.

Placebo-controlled double-blind comparative study on the preventive efficacy of mesna against ifosfamide-induced urinary disorders. OpenUrlCrossRefPubMedHensley ML, Schuchter LM, Lindley C, Meropol NJ, Cohen GI, Broder Hytrin (Terazosin Hcl)- FDA, et al.

American Society of Clinical Oncology clinical practice guidelines for the use of chemotherapy and radiotherapy protectants. OpenUrlCrossRefPubMedReinhold-Keller E, Beuge N, Latza U, de Groot K, Rudert H, Career pfizer B, et al. OpenUrlCrossRefPubMedKoldingsnes W, Gran JT, Omdal R, Husby G. Intravenous pulse administration of cyclophosphamide versus daily oral treatment career pfizer patients with antineutrophil cytoplasmic antibody-associated vasculitis and renal involvement: a prospective, randomized study.

OpenUrlCrossRefPubMedAdu D, Pall A, Luqmani RA, Richards NT, Howie AJ, Emery P, et al. Controlled trial of pulse versus continuous prednisolone and cyclophosphamide in the treatment of systemic vasculitis. Controlled studies of oral immunosuppressive drugs in lupus nephritis.

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